Kinetic analysis of pre-ribosome structure in vivo

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Kinetic analysis of pre-ribosome structure in vivo.

Pre-ribosomal particles undergo numerous structural changes during maturation, but their high complexity and short lifetimes make these changes very difficult to follow in vivo. In consequence, pre-ribosome structure and composition have largely been inferred from purified particles and analyzed in vitro. Here we describe techniques for kinetic analyses of the changes in pre-ribosome structure ...

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ژورنال

عنوان ژورنال: RNA

سال: 2012

ISSN: 1355-8382

DOI: 10.1261/rna.034751.112